I used the year 1975 to start counting region titles. That is when we started talking with some regularity about regions and region titles. Prior to that, one heard of district titles and sectional titles(state semis).
If we wanted to go back to the Stone Ages, Miami High and Coral Gables could make a strong case that they were one of the best 25 large programs in the state. My version in the original post is really meant to be a more modern-day version of such a list. As it is, it feels a bit funny listing a program like Merritt Island, whose heyday was so long ago.